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PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

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PDF] Clearance Prediction Methodology Needs Fundamental

Evidence of the need for modified well-stirred model in vitro to

Use of Segregated Hepatocyte Scaling Factors and Cross-Species

In Vitro - in Vivo Extrapolation of Hepatic Clearance in

Precisely adjusting the hepatic clearance of highly extracted

In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance

Successful and Unsuccessful Prediction of Human Hepatic Clearance for Lead Optimization. - Abstract - Europe PMC

PDF) Clearance Prediction Methodology Needs Fundamental

Utilizing virtual experiments to increase understanding of

Precisely adjusting the hepatic clearance of highly extracted

PDF] Clearance Prediction Methodology Needs Fundamental

In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance

Molecules, Free Full-Text